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Telomerase reverse transcriptase gene amplification in hepatocellular carcinoma

โœ Scribed by YOSHITAKA TAKUMA; KAZUHIRO NOUSO; YOSHIYUKI KOBAYASHI; SHINICHIRO NAKAMURA; HIRONORI TANAKA; EIJI MATSUMOTO; TATSUYA FUJIKAWA; MAYUMI SUZUKI; TADASHI HANAFUSA; YASUSHI SHIRATORI

Book ID
108949917
Publisher
John Wiley and Sons
Year
2004
Tongue
English
Weight
139 KB
Volume
19
Category
Article
ISSN
0815-9319

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โœ Eishiro Mizukoshi; Yasunari Nakamoto; Yohei Marukawa; Kuniaki Arai; Tatsuya Yama ๐Ÿ“‚ Article ๐Ÿ“… 2006 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 453 KB

Human telomerase reverse transcriptase, hTERT, has been identified as the catalytic enzyme required for telomere elongation. hTERT is expressed in most tumor cells but seldom expressed in most human adult cells. It has been reported that 80% to 90% of hepatocellular carcinomas (HCCs) express hTERT,