✦ LIBER ✦

Telomerase: regulation, function and transformation

✍ Scribed by Carolyn K. Dong; Kenkichi Masutomi; William C. Hahn

Book ID: 108110043
Publisher: Elsevier Science
Year: 2005
Tongue: English
Weight: 119 KB
Volume: 54
Category: Article
ISSN: 1040-8428
DOI: 10.1016/j.critrevonc.2004.12.005

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Human telomerase, a ribonucleoprotein that adds TTAGGG repeats onto telomeres and compensates for their shortening, is repressed in most normal human somatic cells. Human somatic cells are considered to have a limited proliferation capacity because of the telomere shortening. Although immortalizatio