A repressor function for telomerase acti
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Motonobu Katoh; Misaki Katoh; Michihiro Kameyama; Hiroyuki Kugoh; Motoyuki Shimi
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Article
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1998
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John Wiley and Sons
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English
⚖ 366 KB
Human telomerase, a ribonucleoprotein that adds TTAGGG repeats onto telomeres and compensates for their shortening, is repressed in most normal human somatic cells. Human somatic cells are considered to have a limited proliferation capacity because of the telomere shortening. Although immortalizatio