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Telomerase activity in `immortal' fish

✍ Scribed by Wolfram Klapper; Klaus Heidorn; Karen Kühne; Reza Parwaresch; Guido Krupp


Book ID
117109663
Publisher
Elsevier Science
Year
1998
Tongue
English
Weight
177 KB
Volume
434
Category
Article
ISSN
0014-5793

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A repressor function for telomerase acti
✍ Motonobu Katoh; Misaki Katoh; Michihiro Kameyama; Hiroyuki Kugoh; Motoyuki Shimi 📂 Article 📅 1998 🏛 John Wiley and Sons 🌐 English ⚖ 366 KB

Human telomerase, a ribonucleoprotein that adds TTAGGG repeats onto telomeres and compensates for their shortening, is repressed in most normal human somatic cells. Human somatic cells are considered to have a limited proliferation capacity because of the telomere shortening. Although immortalizatio