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Telomerase Activity in Gynecologic Tumors

โœ Scribed by Peng-Sheng Zheng; Tsuyoshi Iwasaka; Fumio Yamasaki; Mamoru Ouchida; Masatoshi Yokoyama; Yoshifumi Nakao; Koichi Fukuda; Toshitake Matsuyama; Hajime Sugimori

Book ID
115617050
Publisher
Elsevier Science
Year
1997
Tongue
English
Weight
228 KB
Volume
64
Category
Article
ISSN
0090-8258

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## Background: Shortening of telomeres occurs with each cell division and eventually results in cell death. the activity of telomerase, an enzyme that catalyzes telomere elongation, has been detected in germ cell lines and cancer cells, and has been detected in immortal cell lines but not in normal

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## BACKGROUND. Telomerase activity has been observed in 80 -90% of carcinomas derived from various organs. However, to the authors' knowledge this report is the first assessment of telomerase activity in gastrointestinal stromal tumors (GISTs). ## METHODS. Telomerase activity was analyzed by th

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