## Background: Telomerase is an enzyme that can reconstitute the ends (telomeres) of chromosomes after cell division and thus circumvent the cumulative damage that occurs in normal adult somatic cells during successive mitotic cycles. recently, it has been proposed that this enzyme should, therefor
Telomerase Activity Detected by Quantitative Assay in Bladder Carcinoma and Exfoliated Cells in Urine
โ Scribed by Fedriga, Roberta; Gunelli, Roberta; Nanni, Oriana; Bacci, Francesco; Amadori, Dino; Calistri, Daniele
- Book ID
- 123349098
- Publisher
- Neoplasia Press
- Year
- 2001
- Tongue
- English
- Weight
- 177 KB
- Volume
- 3
- Category
- Article
- ISSN
- 1522-8002
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## METHODS. The authors used a polymerase chain reaction (PCR)-based telomeric repeat amplification protocol (TRAP) assay to determine the presence of te-Department of Urology, Mount Sinai School of lomerase activity in voided urine samples from patients with known but yet un-Medicine, New York, N
## BACKGROUND. Telomerase is a ribonucleoprotein that synthesizes telomeres. It is detected in more than 85% of samples obtained from cancer tissues, including urologic neoplasia. The authors determined telomerase activity semiquantatively and in-cell telomerase activity in exfoliated urothelial c