Early diagnosis is still the most important prerequisite for successful cancer treatment and this holds true for bladder cancer. Urine cytology is commonly used as a non-invasive screening procedure for the detection of bladder carcinoma, but this method is labour-intensive and often generates false
Telomerase activity in solid transitional cell carcinoma, bladder washings, and voided urine
β Scribed by Raymond S. Lance; Wade K. Aldous; Jason Blaser; J.Brantley Thrasher
- Book ID
- 117724756
- Publisher
- Elsevier Science
- Year
- 1998
- Tongue
- English
- Weight
- 559 KB
- Volume
- 4
- Category
- Article
- ISSN
- 1078-1439
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## METHODS. The authors used a polymerase chain reaction (PCR)-based telomeric repeat amplification protocol (TRAP) assay to determine the presence of te-Department of Urology, Mount Sinai School of lomerase activity in voided urine samples from patients with known but yet un-Medicine, New York, N
## Background: Telomerase activity is not detectable in normal cells, and their telomers shorten until the chromosome is unable to replicate. immortal cells have short but stable chromosomes and increased telomerase activity. transitional cell carcinoma (tcc) has only a few useful markers of diagno