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Technical evaluation of thymidine kinase assay in cytosols from breast cancers

โœ Scribed by Romain, S.; Spyratos, F.; Guirou, O.; Deytieux, S.; Chinot, O.; Martin, P.M.


Book ID
122956155
Publisher
Elsevier Science
Year
1994
Tongue
English
Weight
399 KB
Volume
30
Category
Article
ISSN
0959-8049

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Prognostic value of cytosolic thymidine
โœ Sylvie Romain; Ib J. Christensen; Olivier Chinot; Ingegerd Balslev; Carsten Rose ๐Ÿ“‚ Article ๐Ÿ“… 1995 ๐Ÿ› John Wiley and Sons ๐ŸŒ French โš– 615 KB

Thymidine kinase (TK) is involved in DNA synthesis by the salvage pathway. In this study, thymidine kinase (TK) was determined in routinely prepared cytosols of primary tumors from 290 breast-cancer patients. Enzyme activity was measured using a radioenzymatic method optimized for detection of the f