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Technetium-99m-labeled monoclonal antibodies for immunoscintigraphy: Simplified preparation and evaluation

✍ Scribed by Mathew L. Thakur; Joseph D. DeFulvio

Book ID
118902142
Publisher
Elsevier Science
Year
1991
Tongue
English
Weight
730 KB
Volume
137
Category
Article
ISSN
0022-1759

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## Abstract The present study refers to the preparation of a 99m‐Technetium labelled murine monoclonal antibody for clinical application. The monoclonal antibody was incubated with a 20fold molar excess of 2‐iminothiolane. The free thiol groups created, were capable of binding reduced technetium. L