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Tec family of protein-tyrosine kinases: an overview of their structure and function

✍ Scribed by Hiroyuki Mano

Book ID
117757877
Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
221 KB
Volume
10
Category
Article
ISSN
1359-6101

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## Abstract Cytoplasmic protein‐tyrosine kinases (PTKs) are enzymes involved in transducing a vast number of signals in metazoans. The importance of the Tec family of kinases was immediately recognized when, in 1993, mutations in the gene encoding Bruton's tyrosine kinase (Btk) were reported to cau