Unlike other solid organ transplants, intestinal transplantation (IT) remains a highly experimental procedure. Rejection, sepsis, and graft-versus-host disease have been the major barriers to successful IT in humans. These problems can be studied in the rat model, but this requires a reliable surgic
Teaching intestinal transplantation in the rat for medical student
✍ Scribed by Flávio Henrique Ferreira Galvão; Telesforo Bacchella; Marcel Cerqueira Machado
- Publisher
- John Wiley and Sons
- Year
- 2007
- Tongue
- English
- Weight
- 208 KB
- Volume
- 27
- Category
- Article
- ISSN
- 0738-1085
No coin nor oath required. For personal study only.
✦ Synopsis
Abstract
Technical difficulties hamper the widespread use of intestinal transplantation in rats. We evaluated the feasibility in training this microsurgical model for medical students. Thirty eight students were assessed. After information about intestinal transplantation in rats, they spontaneously agreed to be trained for this procedure. The course consisted of 4‐h weekly lessons during 4‐month period. The teaching process includes assessment in four phases: I) conception of intestinal transplantation and rat anatomy; II) basic microsurgery training; III) donor operation; IV) donor/recipient operation. Wistar rats were used as donors and recipients in one‐step small bowel transplantation. All students (100%) reached phase II, seven students (18.42%) reached phase III and two students (5.26%) reached phase IV. Decreased interest about the theme, lack of time and patience, frustration and/or inability were all reasons given by the student that may have contributed to the low rate of success. Medical students achieved a low rate of completion for training in rat intestinal transplantation microsurgical procedures. © 2007 Wiley‐Liss, Inc. Microsurgery 2007.
📜 SIMILAR VOLUMES
Transplantation of small bowel and colon has been recently advocated, aiming to prevent dehydration, reduce stoma output, and promote earlier post-transplant weaning from parental nutrition. 1 Some patients needing intestinal transplantation may also have anorectal dysfunction or a permanent colosto
## Abstract Simultaneous liver transplantation may reduce the risk of intestinal transplant rejection. We have recently developed two new models of combined liver/intenstine transplantation (LIT) in the rat to study this phenomenon. Herein, we report our experience with LIT using a single donor (SD
## Abstract For the purpose of immunological study on small intestinal transplantation (SIT), rat SIT models using direct suture technique widely have been used, which requires at least several months of training for microsurgery. Alternatively, a simple cuff technique for SIT has been mainly used