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TCR-Mediated Internalization of Peptide-MHC Complexes Acquired by T Cells

✍ Scribed by Huang, J.


Book ID
121161720
Publisher
American Association for the Advancement of Science
Year
1999
Tongue
English
Weight
526 KB
Volume
286
Category
Article
ISSN
0036-8075

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Antigen-specific T-cell activation requires the formation of a transient cell-cell conjugate between a T cell and an appropriate antigen presenting cell (APC). Focal aggregation of T-cell receptor (TCR) molecules at the T-cell-APC membrane interface accompanies formation of multiple non-covalent int