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Peptide specific expansion of CD8+ T cells by recombinant plate bound MHC/peptide complexes

✍ Scribed by Esben G.W. Schmidt; Søren Buus; Mette Thorn; Anette Stryhn; Christian Leisner; Mogens H. Claesson


Book ID
113717613
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
685 KB
Volume
340
Category
Article
ISSN
0022-1759

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## Abstract We have characterized three different programs of activation for alloreactive CD8 T cells expressing the BM3.3 TCR, their elicitation depending on the characteristics of the stimulating peptide/MHC complex. The high‐affinity interaction between the TCR and the K^b^‐associated endogenous