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CD8 Expression Allows T Cell Signaling by Monomeric Peptide-MHC Complexes

✍ Scribed by Jérôme Delon; Claude Grégoire; Bernard Malissen; Sylvie Darche; Fabrice Lemaître; Philippe Kourilsky; Jean-Pierre Abastado; Alain Trautmann

Book ID
117722964
Publisher
Elsevier Science
Year
1998
Tongue
English
Weight
118 KB
Volume
9
Category
Article
ISSN
1074-7613

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Distinct orientation of the alloreactive
Distinct orientation of the alloreactive monoclonal CD8 T cell activation program by three different peptide/MHC complexes
✍ Nathalie Auphan-Anezin; Catherine Mazza; Annick Guimezanes; Gregory A. Barrett-W 📂 Article 📅 2006 🏛 John Wiley and Sons 🌐 English ⚖ 489 KB

## Abstract We have characterized three different programs of activation for alloreactive CD8 T cells expressing the BM3.3 TCR, their elicitation depending on the characteristics of the stimulating peptide/MHC complex. The high‐affinity interaction between the TCR and the K^b^‐associated endogenous