Tautomerism and hydrogen bonding in bilirubin and biliverdin
โ Scribed by Nichol, A.W.; Morell, D.B.
- Book ID
- 123253971
- Publisher
- Elsevier Science
- Year
- 1969
- Tongue
- English
- Weight
- 595 KB
- Volume
- 177
- Category
- Article
- ISSN
- 0304-4165
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๐ SIMILAR VOLUMES
## Abstract A simple method is described for the preparation of [^3^H]bilirubin IXโฮฑ by the reduction of biliverdin IXโฮฑ using sodium boro[^3^H]hydride. The [^3^H]bilirubin is obtained with a high specific radioactivity and the tritium is located at the methylene bridge (Cโ10). Oxidation of the [^3
The 13 C cross-polarization magic angle spinning NMR spectra of N-( ) indicate a keto-hydroxy tautomerism of 1 but not of 2. This was confirmed by a single-crystal x-ray diffraction study of 1, which revealed that the two distinct molecules in the unit cell are linked by intermolecular hydrogen bon