Synthesis of biliverdin and bilirubin glucuronides
โ Scribed by Frans Compernolle
- Book ID
- 115911297
- Publisher
- Elsevier Science
- Year
- 1980
- Tongue
- English
- Weight
- 346 KB
- Volume
- 114
- Category
- Article
- ISSN
- 0014-5793
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๐ SIMILAR VOLUMES
## Abstract A simple method is described for the preparation of [^3^H]bilirubin IXโฮฑ by the reduction of biliverdin IXโฮฑ using sodium boro[^3^H]hydride. The [^3^H]bilirubin is obtained with a high specific radioactivity and the tritium is located at the methylene bridge (Cโ10). Oxidation of the [^3
Neutral solvent systems were developed to isolate the alpha, beta, gamma, and delta isomers of biliverdin IX dimethyl ester by TLC. The individual free acids of biliverdin IX were obtained by saponification of the corresponding dimethyl esters. The bilirubin IX isomers were prepared by reducing the