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Targeting tumor cells with bispecific antibodies and T cells

โœ Scribed by D.M Kranz; T.C Manning; L.A Rund; B.K Cho; M.M Gruber; E.J Roy

Book ID
114163447
Publisher
Elsevier Science
Year
1998
Tongue
English
Weight
295 KB
Volume
53
Category
Article
ISSN
0168-3659

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โœ Edward J. Roy; Bryan K. Cho; Laurie A. Rund; Todd A. Patrick; David M. Kranz ๐Ÿ“‚ Article ๐Ÿ“… 1998 ๐Ÿ› John Wiley and Sons ๐ŸŒ French โš– 156 KB

High-affinity receptors expressed on the surface of some tumors can be exploited by chemically conjugating the ligand for the receptor and an antibody against immune effector cells, thus redirecting their cytolytic potential against the tumor. Ovarian carcinomas and some brain tumors express the hig