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Targeting the RAF/MEK/ERK, PI3K/AKT and P53 pathways in hematopoietic drug resistance

โœ Scribed by James A. McCubrey; Linda S. Steelman; Richard A. Franklin; Steven L. Abrams; William H. Chappell; Ellis W.T. Wong; Brian D. Lehmann; David M. Terrian; Jorg Basecke; Franca Stivala; Massimo Libra; Camilla Evangelisti; Alberto M. Martelli

Book ID
113418928
Publisher
Elsevier Science
Year
2007
Tongue
English
Weight
1005 KB
Volume
47
Category
Article
ISSN
0065-2571

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## Abstract Chemotherapy remains a commonly used therapeutic approach for many cancers. Indeed chemotherapy is relatively effective for treatment of certain cancers and it may be the only therapy (besides radiotherapy) that is appropriate for certain cancers. However, a common problem with chemothe