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Targeting the mTOR Signaling Network for Cancer Therapy

✍ Scribed by Meric-Bernstam, F.; Gonzalez-Angulo, A. M.

Book ID
124080143
Publisher
American Society of Clinical Oncology
Year
2009
Tongue
English
Weight
655 KB
Volume
27
Category
Article
ISSN
0732-183X

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The mammalian target of rapamycin (mTOR) is a highly conserved serine/threonine kinase that can sense environmental stimuli such as growth factors, energy state, and nutrients. It is essential for cell growth, proliferation, and metabolism, but dysregulation of mTOR signaling pathway is also associa