Targeting the mTOR Signaling Network for
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Wang, Chong; Yu, Jin-Tai; Miao, Dan; Wu, Zhong-Chen; Tan, Meng-Shan; Tan, Lan
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Article
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2013
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Springer
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English
⚖ 622 KB
The mammalian target of rapamycin (mTOR) is a highly conserved serine/threonine kinase that can sense environmental stimuli such as growth factors, energy state, and nutrients. It is essential for cell growth, proliferation, and metabolism, but dysregulation of mTOR signaling pathway is also associa