𝔖 Bobbio Scriptorium
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Targeting Tankyrase 1 as a therapeutic strategy for BRCA-associated cancer

✍ Scribed by McCabe, N; Cerone, M A; Ohishi, T; Seimiya, H; Lord, C J; Ashworth, A


Book ID
109970818
Publisher
Nature Publishing Group
Year
2009
Tongue
English
Weight
203 KB
Volume
28
Category
Article
ISSN
0950-9232

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## Abstract Recent studies implicate that the estrogen receptor (ER) coregulator proline‐, glutamic acid‐, and leucine‐rich protein (PELP) 1 as playing critical roles in ER‐genomic, ER‐nongenomic, and ER‐signaling cross talk with growth factor signaling pathways. PELP1 expression is deregulated in