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Targeting plasma cells improves detection of cytogenetic aberrations in multiple myeloma: phenotype/genotype fluorescence in situ hybridization

✍ Scribed by Marilyn L. Slovak; Victoria Bedell; Kristen Pagel; Karen L. Chang; David Smith; George Somlo


Book ID
113512662
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
420 KB
Volume
158
Category
Article
ISSN
0165-4608

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## Abstract ## BACKGROUND Monoclonal gammopathy of undetermined significance (MGUS) is a clonal plasma cell (PC) disorder usually characterized by a benign clinical course. However, in approximately 25% of patients, the disorder has been found to evolve into a multiple myeloma (MM). The mechanism