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Cytogenetic and fluorescence in situ hybridization studies in 60 patients with multiple myeloma and plasma cell leukemia

✍ Scribed by Elisabet Lloveras; Isabel Granada; Lurdes Zamora; Blanca Espinet; Lourdes Florensa; Carles Besses; Marisol Xandri; Maria Encarnación Pérez-Vila; Fuensanta Millà; Soledad Woessner; Francesc Solé


Book ID
114135698
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
106 KB
Volume
148
Category
Article
ISSN
0165-4608

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Comparative genomic hybridization (CGH) was used to identify recurrent regions of DNA sequence loss and gain in 21 multiple myeloma (MM) and plasma cell leukemia (PCL) primary tumor specimens and cell lines. Multiple regions of non-random sequence loss and gain were observed in 8/8 primary advanced