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Targeting Matrix Metalloproteinases in Human Prostate Cancer

✍ Scribed by QINGXIANG AMY SANG; MARTIN A. SCHWARTZ; HUI LI; LELAND W.K CHUNG; HAIYEN E. ZHAU


Book ID
111395044
Publisher
John Wiley and Sons
Year
1999
Tongue
English
Weight
372 KB
Volume
878
Category
Article
ISSN
0890-6564

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## Abstract Degradation of extracellular matrix is crucial for malignant tumour growth, invasion, metastasis and angiogenesis. Matrix metalloproteinases (MMPs) are a family of zinc‐dependent neutral endopeptidases collectively capable of degrading essentially all matrix components. Elevated levels