1,25 dihydroxyvitamin D3, the active form of vitamin D, has immunomodulatory properties in vitro and in vivo. We report that treatment with 1,25 dihydroxyvitamin 03 (5 gg/kg on alternate days) prevents the development of clinical diabetes in NOD mice, an animal model of human autoimmune diabetes. Di
β¦ LIBER β¦
Targeting JAK3 with JANEX-1 for prevention of autoimmune type 1 diabetes in NOD mice
β Scribed by Marina Cetkovic-Cvrlje; Angela L Dragt; Alexei Vassilev; Xing-Ping Liu; Fatih M Uckun
- Book ID
- 117792892
- Publisher
- Elsevier Science
- Year
- 2003
- Tongue
- English
- Weight
- 502 KB
- Volume
- 106
- Category
- Article
- ISSN
- 1090-2341
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
Prevention of autoimmune diabetes in NOD
β
C. Mathieu; M. Waer; J. Laureys; O. Rutgeerts; R. Bouillon
π
Article
π
1994
π
Springer
π
English
β 794 KB
Targeting a Primary Trimolecular Complex
β
Li Zhang; Taylor Armstrong; Kelly Johnson; Brian Stadinski; George Eisenbarth
π
Article
π
2010
π
Elsevier Science
π
English
β 44 KB
Prevention of development of type 1 diab
β
Marina Cetkovic-Cvrlje; Angela L Dragt; Fatih M Uckun
π
Article
π
2000
π
Elsevier Science
π
English
β 128 KB
Immunization with an insulin peptideβMHC
β
Li Zhang; Brian D. Stadinski; Aaron Michels; John W. Kappler; George S. Eisenbar
π
Article
π
2011
π
John Wiley and Sons
π
English
β 535 KB
## Abstract ## Background Mutating the insulin B:9β23 peptide prevents diabetes in NOD mice. Thus, the trimolecular complex of IβA$^{\rm{g7}}$βinsulin B:9β23 peptideβTCR may be essential for the development of spontaneous diabetes. Pathogenic T cells recognize the B:9β23 peptide presented by IβA$^
Development of Multivalent Vaccine for T
β
Lin, M.S.
π
Article
π
2009
π
Elsevier Science
π
English
β 39 KB
Interleukin-21 Is Required for the Devel
β
Sutherland, A. P.R.; Van Belle, T.; Wurster, A. L.; Suto, A.; Michaud, M.; Zhang
π
Article
π
2009
π
American Diabetes Association
π
English
β 816 KB