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Targeting in linear DNA duplexes with two complementary probe strands for hybrid stability

✍ Scribed by Sena, Elissa P.; Zarling, David A.


Book ID
109915662
Publisher
Nature Publishing Group
Year
1993
Tongue
English
Weight
911 KB
Volume
3
Category
Article
ISSN
1061-4036

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## Abstract __The fluorescent 8‐aza‐2′‐deoxyisoguanosine (**4**) as well as the parent 2′‐deoxyisoguanosine (**1**) were used as protonated dCH^+^ surrogates in the third strand of oligonucleotide triplexes. Stable triplexes were formed by Hoogsteen base pairing. In contrast to dC, triplexes contai