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Targeting fibroblast growth factor receptor 3 enhances radiosensitivity in human squamous cancer cells

✍ Scribed by Uzawa, K; Ishigami, T; Fushimi, K; Kawata, T; Shinozuka, K; Kasamatsu, A; Sakamoto, Y; Ogawara, K; Shiiba, M; Bukawa, H


Book ID
109972838
Publisher
Nature Publishing Group
Year
2011
Tongue
English
Weight
473 KB
Volume
30
Category
Article
ISSN
0950-9232

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Zhang et al. recently reported an activating mutation of the receptor tyrosine kinase fibroblast growth factor receptor 3 in 62% of 71 oral squamous cell carcinomas (OSCC). 1 More than 300,000 new cases of OSCC are diagnosed annually, worldwide. This aggressive epithelial cancer is associated with s