Overexpression of basic fibroblast growth factor confers negative growth regulation and radiosensitization in human breast cancer cells
β Scribed by Eyal Fenig; Robert Wieder; Ralph Maxy; Zvi Fuks; Joachim Yahalom
- Publisher
- Elsevier Science
- Year
- 1994
- Tongue
- English
- Weight
- 143 KB
- Volume
- 30
- Category
- Article
- ISSN
- 0360-3016
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
Basic fibroblast growth factor (bFGF, FGF-2) is progressively lost from mammary epithelial cells as they become malignant. To investigate the effects of restoring the expression of bFGF in breast cancer cells, we constructed MCF-7 cells that permanently overexpress 18-kD cytoplasm-localizing bFGF (M
Basic fibroblast growth factor (bFGF) and transforming growth factor beta 1 (TGFP1) are potential autocrine growth regulators of the prostatic stroma, and therefore may play a role in the development of benign prostatic hyperplasia (BPH). We reported [Story et al.: Prostate 22:183-197, 19931 that TG
The growth of capillary endothelial cells (BCE) is an important regulatory step in the formation of capillary blood vessels. In vivo, the proliferation of these cells is stringently controlled. In vitro they can be stimulated by polypeptide growth factors, such as acidic fibroblast growth factor (aF