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Targeting epigenetic abnormalities with histone deacetylase inhibitors

✍ Scribed by Barbara A. Conley; John J. Wright; Shivaani Kummar


Publisher
John Wiley and Sons
Year
2006
Tongue
English
Weight
136 KB
Volume
107
Category
Article
ISSN
0008-543X

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## Abstract Hepatocellular carcinoma (HCC) ranks in prevalence and mortality among top 10 cancers worldwide. Butyric acid (BA), a member of histone deacetylase inhibitors (HDACi) has been proposed as an anticarcinogenic agent. However, its short half‐life is a therapeutical limitation. This problem