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Targeting adenovirus

✍ Scribed by Wickham, T J

Book ID: 110038614
Publisher: Nature Publishing Group
Year: 2000
Tongue: English
Weight: 99 KB
Volume: 7
Category: Article
ISSN: 0969-7128
DOI: 10.1038/sj.gt.3301115

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## Abstract Adenoviruses (Ads) are the most frequently used viral vectors in gene therapy and cancer therapy. Obstacles to successful clinical application include accumulation of vector and transduction in liver cells, coupled with poor transduction of target cells and tissues such as tumours. Many