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Targeted vascular delivery of antisense molecules using intravenous microbubbles

✍ Scribed by Thomas R. Porter; Feng Xie; Derek Knapp; Patrick Iversen; Luis A. Marky; Jeane M. Tsutsui; Souvik Maiti; John Lof; Stanley J. Radio; Nicholas Kipshidze

Book ID: 116342977
Publisher: Elsevier Science
Year: 2006
Tongue: English
Weight: 990 KB
Volume: 7
Category: Article
ISSN: 1553-8389
DOI: 10.1016/j.carrev.2005.10.010

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## Abstract ## Background Ultrasound/microbubble‐mediated gene delivery has the potential to be targeted to tissue deep in the body by directing the ultrasound beam following vector administration. Application of this technology would be minimally invasive and benefit from the widespread clinical