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Systemic targeted delivery of antisense with perflourobutane gas microbubble carrier reduced neointimal formation in the porcine coronary restenosis model

✍ Scribed by Nicholas N. Kipshidze; Thomas R. Porter; George Dangas; Hamid Yazdi; Fermin Tio; Feng Xie; David Hellinga; Jana Fournadjiev; Roswitha Wolfram; Rufus Seabron; Ron Waksman; Alexander Abizaid; Gary Roubin; Sriram Iyer; Martin B. Leon; Jeffrey W. Moses; Patrick Iversen


Book ID
114411666
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
417 KB
Volume
4
Category
Article
ISSN
1522-1865

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Advanced c-myc antisense (AVI-4126)-elut
✍ Nicholas N. Kipshidze; Patrick Iversen; Han-Soo Kim; Hamid Yiazdi; George Dangas πŸ“‚ Article πŸ“… 2004 πŸ› John Wiley and Sons 🌐 English βš– 349 KB

## Abstract An advanced six‐ring morpholino backbone c‐myc antisense (AVI‐4126) was shown to inhibit c‐myc expression and intimal hyperplasia after local catheter delivery in a porcine balloon injury model. The purpose of this study was to investigate the effects of an AVI‐4126‐eluting phosphorylch