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Intramural coronary delivery of advanced antisense oligonucleotides reduces neointimal formation in the porcine stent restenosis model

✍ Scribed by Nicholas N Kipshidze; Han-Soo Kim; Patrick Iversen; Hamid A Yazdi; Balram Bhargava; Gishel New; Roxana Mehran; Fermin Tio; Christian Haudenschild; George Dangas; Gregg W Stone; Sriram Iyer; Gary S Roubin; Martin B Leon; Jeffrey W Moses


Book ID
119542933
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
852 KB
Volume
39
Category
Article
ISSN
1558-3597

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Advanced c-myc antisense (AVI-4126)-elut
✍ Nicholas N. Kipshidze; Patrick Iversen; Han-Soo Kim; Hamid Yiazdi; George Dangas πŸ“‚ Article πŸ“… 2004 πŸ› John Wiley and Sons 🌐 English βš– 349 KB

## Abstract An advanced six‐ring morpholino backbone c‐myc antisense (AVI‐4126) was shown to inhibit c‐myc expression and intimal hyperplasia after local catheter delivery in a porcine balloon injury model. The purpose of this study was to investigate the effects of an AVI‐4126‐eluting phosphorylch