Targeted toxins as anticancer agents
โ Scribed by Clay B. Siegall
- Publisher
- John Wiley and Sons
- Year
- 1994
- Tongue
- English
- Weight
- 717 KB
- Volume
- 74
- Category
- Article
- ISSN
- 0008-543X
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
## Abstract For Abstract see ChemInform Abstract in Full Text.
Preparation of a series of substituted 4-thiazolylmethoxyureas and 4-thiazolylmethoxythioureas is described. These compounds, which are structurally related to the antitumor agent hydroxyurea, were essentially inactive when screened against the L-1210 lymphoid leukemia test system. One compound, 4th
## Abstract Five licofelone ([2,2โdimethylโ6โ(4โchlorophenyl)โ7โphenylโ2,3โdihydroโ1__H__โpyrrolizinโ5โyl]acetic acid) nitric oxide donor conjugates were developed by a parallel synthesis approach. The biological screening revealed that compounds with a propyl (**6b**), butyl (**6c**), or octyl (**