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4-Thiazolylmethoxyureas as potential anticancer agents

✍ Scribed by Glenn H. Hamor; Andon Hudaverdi

Publisher
John Wiley and Sons
Year
1970
Tongue
English
Weight
226 KB
Volume
59
Category
Article
ISSN
0022-3549

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✦ Synopsis

Preparation of a series of substituted 4-thiazolylmethoxyureas and 4-thiazolylmethoxythioureas is described. These compounds, which are structurally related to the antitumor agent hydroxyurea, were essentially inactive when screened against the L-1210 lymphoid leukemia test system. One compound, 4thiazolylmethoxyurea, showed moderate anti-inflammatory activity in the carrageenin-induced rat paw edema test.

Keyphrases 0 Anticancer agents, potential-synthesis [7 4-Thiazolylmethoxyureas-synthesis CI Pharmacological screening-4-thiazolylmethoxyureas [7 IR spectrophotometry-identity

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