## Abstract In order to identify genes or regions involved in nonsyndromic cleft lip with or without cleft palate (CL/P) in families from India, we analyzed 38 multiplex families (DNA from 272 individuals, 82 affected with CL/P, 190 unaffected) for 285 genomeβwide markers (average spacing 12.6 cM),
Targeted scan of fifteen regions for nonsyndromic cleft lip and palate in Filipino families
β Scribed by Schultz, R.E. ;Cooper, M.E. ;Daack-Hirsch, S. ;Shi, M. ;Nepomucena, B. ;Graf, K.A. ;O'Brien, E.K. ;O'Brien, S.E. ;Marazita, M.L. ;Murray, J.C.
- Publisher
- John Wiley and Sons
- Year
- 2004
- Tongue
- English
- Weight
- 76 KB
- Volume
- 125A
- Category
- Article
- ISSN
- 0148-7299
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## Abstract Cleft lip with or without cleft palate (CL/P) is a common congenital anomaly, with birth prevalence ranging from 1/500 to 1/1,000. A number of genetic loci have shown positive linkage or association results in European Caucasian populations. The purpose of the current study was to asses
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## Abstract Nonsyndromic cleft lip with or without cleft palate is a common birth defect with a wide range of prevalence among different populations, apparently highest in Asians and Amerindians and lowest in Africans. Recent genomewide association studies of Europeanβderived and Asian populations