The design and synthesis of non-peptide
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David C. Horwell; Andrew I. Morrell; Edward Roberts
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Article
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1996
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Elsevier Science
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English
⚖ 112 KB
2,4-disubstituted morpholin-3-one based ligands which show affinity for tachykinin receptors have been designed and synthesised. Variation of the side chains attached to the central template gives rise to selectivity between receptor subtypes. This selectivity is directly analogous to that exhibited