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Targeted Genome Modification via Triple Helix Formation

โœ Scribed by JENNIFER M. KALISH; PETER M. GLAZER


Book ID
111479776
Publisher
John Wiley and Sons
Year
2005
Tongue
English
Weight
427 KB
Volume
1058
Category
Article
ISSN
0890-6564

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New self-assembled network of plasmid DNA was prepared via both photo-crosslinking and triple helix formations, and evaluated the conformation of DNA network by electrophoresis. Two kinds of TFO sequences were designed to form the triple helix with pUC19 at different positions. In addition to the tr