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Targeted Gene Repair Facilitated by Peptide Nucleic Acids (PNA)

✍ Scribed by Prof. Dr. Peter E. Nielsen


Publisher
John Wiley and Sons
Year
2010
Tongue
English
Weight
182 KB
Volume
11
Category
Article
ISSN
1439-4227

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Olefinic Peptide Nucleic Acids (OPAs): N
✍ Rolf SchΓΌtz; Michel Cantin; Christopher Roberts; Beate Greiner; Eugen Uhlmann; C πŸ“‚ Article πŸ“… 2000 πŸ› John Wiley and Sons 🌐 English βš– 116 KB πŸ‘ 2 views

Polyamide or peptide nucleic acids (PNAs), first described in 1991, [1] are DNA analogues based entirely on an achiral polyamide backbone (Scheme 1). The PNAs undergo sequence-specific and efficient Watson Β± Crick base pairing with Scheme 1. Sections of the chemical structures of deoxyribonucleic ac