Olefinic Peptide Nucleic Acids (OPAs): N
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Rolf SchΓΌtz; Michel Cantin; Christopher Roberts; Beate Greiner; Eugen Uhlmann; C
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Article
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2000
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John Wiley and Sons
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English
β 116 KB
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Polyamide or peptide nucleic acids (PNAs), first described in 1991, [1] are DNA analogues based entirely on an achiral polyamide backbone (Scheme 1). The PNAs undergo sequence-specific and efficient Watson Β± Crick base pairing with Scheme 1. Sections of the chemical structures of deoxyribonucleic ac