✦ LIBER ✦
Olefinic Peptide Nucleic Acids (OPAs): New Aspects of the Molecular Recognition of DNA by PNA
✍ Scribed by Rolf Schütz; Michel Cantin; Christopher Roberts; Beate Greiner; Eugen Uhlmann; Christian Leumann
- Publisher
- John Wiley and Sons
- Year
- 2000
- Tongue
- English
- Weight
- 116 KB
- Volume
- 39
- Category
- Article
- ISSN
- 0044-8249
No coin nor oath required. For personal study only.
✦ Synopsis
Polyamide or peptide nucleic acids (PNAs), first described in 1991, [1] are DNA analogues based entirely on an achiral polyamide backbone (Scheme 1). The PNAs undergo sequence-specific and efficient Watson ± Crick base pairing with Scheme 1. Sections of the chemical structures of deoxyribonucleic acids (DNAs), polyamide or peptide nucleic acids (PNAs), and (E)-and (Z)olefinic polyamide nucleic acids ((E)-and (Z)-OPAs).