Target cell-dependent T cell-mediated lysis of vaccinia virus-infected cells
β Scribed by U. Koszinowski; R. Thomssen
- Publisher
- John Wiley and Sons
- Year
- 1975
- Tongue
- English
- Weight
- 748 KB
- Volume
- 5
- Category
- Article
- ISSN
- 0014-2980
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Cytotoxic T lymphocytes secrete a pore-forming cytolysin, perforin, that damages membranes of target cells. They also ligate Fas receptors on target cells and provoke apoptotic death. A20 (B lymphoma) and P815 (mastocytoma) cell lines were examined for their susceptibility to perforin-mediated lysis