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TANK is a negative regulator of Toll-like receptor signaling and is critical for the prevention of autoimmune nephritis

✍ Scribed by Kawagoe, Tatsukata; Takeuchi, Osamu; Takabatake, Yoshitsugu; Kato, Hiroki; Isaka, Yoshitaka; Tsujimura, Tohru; Akira, Shizuo


Book ID
109920814
Publisher
Nature Publishing Group
Year
2009
Tongue
English
Weight
585 KB
Volume
10
Category
Article
ISSN
1529-2908

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Type 1 insulin-like growth factor recept
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## Abstract Type 1 insulin‐like growth factor receptor (IGF1R) signaling in neuronal development was studied in mutant mice with blunted __igf1r__ gene expression in nestin‐expressing neuronal precursors. At birth [postnatal (P) day 0] brain weights were reduced to 37% and 56% of controls in mice h