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Tanespimycin pharmacokinetics: a randomized dose-escalation crossover phase 1 study of two formulations

โœ Scribed by Howard A. Burris; David Berman; Bindu Murthy; Suzanne Jones


Book ID
105993518
Publisher
Springer
Year
2010
Tongue
English
Weight
394 KB
Volume
67
Category
Article
ISSN
0344-5704

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## Background Interferon (IFN) alpha conjugation to polyethylene glycol (PEG) results in a better pharmacokinetic profile and efficacy. The aim of this study was to compare the pharmacokinetic, pharmacodynamic and safety properties of a new, locally developed, 40-kDa PEG-IFN alpha-2b preparation wi