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Tandem synthesis of 1-(alkylamino)-2,4-diarylpyrimido[6,1-a]isoquinolin-5-ium chlorides from isoquinoline, N-alkyl-benzimidoyl chlorides, and isocyanides

✍ Scribed by Issa Yavari; Gholamhossein Khalili; Anvar Mirzaei

Book ID: 104097296
Publisher: Elsevier Science
Year: 2010
Tongue: French
Weight: 176 KB
Volume: 51
Category: Article
ISSN: 0040-4039
DOI: 10.1016/j.tetlet.2009.12.097

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✦ Synopsis

N-Alkyl-benzimidoyl chloride Tandem reaction a b s t r a c t 1-(Alkylamino)-2,4-diarylpyrimido[6,1-a]isoquinolin-5-ium chlorides are obtained in good yields via a tandem reaction between isoquinoline, N-alkyl-benzimidoyl chlorides and alkyl isocyanides in anhydrous acetonitrile.

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