Tandem Diels−Alder/Fragmentation Approach to the Synthesis of Eleutherobin
✍ Scribed by Winkler, Jeffrey D.; Quinn, Kevin J.; MacKinnon, Colin H.; Hiscock, Steven D.; McLaughlin, Emily C.
- Book ID
- 120337886
- Publisher
- American Chemical Society
- Year
- 2003
- Tongue
- English
- Weight
- 105 KB
- Volume
- 5
- Category
- Article
- ISSN
- 1523-7060
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📜 SIMILAR VOLUMES
The application of the transannular Diels-Alder strategy on macrocyclic trienes having the trans-trans-cis olefin geometry led to trans-syn-trans tricycles which are advanced intermediates for the synthesis of natural products like Momilactone A.
## Abstract The 2,5‐dimethylidene‐3,6‐bis[(__Z__)‐(2‐nitrophenyl)sulfenylmethylidene]‐7‐oxabicyclo[2.2.1]heptane (**13**) can be used to generate polyfunctional and multicyclic molecules with high regio‐ and stereoselectivity __via__ two successive __Diels__‐__Alder__ additions using two different