Tamoxifen treatment failures in hormonally responsive breast cancers correlation with steroid receptors
β Scribed by Norman D. Bloom; Jerry H. Fishman
- Publisher
- John Wiley and Sons
- Year
- 1983
- Tongue
- English
- Weight
- 430 KB
- Volume
- 51
- Category
- Article
- ISSN
- 0008-543X
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Estrogen receptors in breast tumors were assayed in 55 premenopausal women undergoing bilateral oophorectomy and in 120 postmenopausal women undergoing bilateral adrenalectomy for treatment of metastatic breast cancer. The data show that 20 (60%) of the 32 patients with estrogen receptor-positive (E
Results of estrogen receptor (ER) and progesterone receptor (PgR) ligand-binding assays (LBAs) are strongly correlated with ER and PgR by immuno-histochemistry (IHC). To investigate whether ER and PgR by IHC are also strongly correlated with tamoxifen response, time to treatment failure (TTF) and ov