This review presents our experience with the use of estrogen receptors (ER) and progesterone receptors (PgR) in the prediction of response to endocrine therapy in stage IV breast cancer. Presence of ER (>3 fmoUmg cytosol protein) significantly predicted response to the antiestrogen tamoxifen and to
โฆ LIBER โฆ
The value of estrogen and progesterone receptor determinations in advanced breast cancer. Estrogen receptor level but not progesterone receptor level correlates with response to tamoxifen
โ Scribed by Werner Robert Bezwoda; Jan D. Esser; Roger Dansey; Ivan Kessel; Myron Lange
- Publisher
- John Wiley and Sons
- Year
- 1991
- Tongue
- English
- Weight
- 460 KB
- Volume
- 68
- Category
- Article
- ISSN
- 0008-543X
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Results of estrogen receptor (ER) and progesterone receptor (PgR) ligand-binding assays (LBAs) are strongly correlated with ER and PgR by immuno-histochemistry (IHC). To investigate whether ER and PgR by IHC are also strongly correlated with tamoxifen response, time to treatment failure (TTF) and ov