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Tamoxifen inhibition of protein kinase C

โœ Scribed by Horgan, K.; Cooke, Eryl; Hallett, M.B.; Mansel, R.E.

Book ID
122339880
Publisher
Elsevier Science
Year
1986
Weight
178 KB
Volume
22
Category
Article
ISSN
0277-5379

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BACKGROUND. Inhibition of protein kinase C (PKC) and modulation of transforming growth factor-โค (TGF-โค) are both associated with tamoxifen treatment, and both appear to be important in the regulation of prostate cancer cell growth. Investigations were performed which sought to measure the efficacy,