## Abstract We generated two complementary systems for Creβmediated recombination of target genes in the mouse digestive epithelium and tested them with a Creβreporter mouse strain. Cre was expressed under the control of a 9 kb regulatory region of the murine villin gene (vilβCre). Genetic recombin
Tamoxifen-inducible Cre-mediated recombination in adipocytes
β Scribed by Antonia Sassmann; Stefan Offermanns; Nina Wettschureck
- Publisher
- John Wiley and Sons
- Year
- 2010
- Tongue
- English
- Weight
- 833 KB
- Volume
- 48
- Category
- Article
- ISSN
- 1526-954X
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
## Abstract Summary: Organβspecific expression of a __Cre__ recombinase allows the analysis of gene function in a particular tissue or cell type. Using a 6.1 kb promoter from the mouse __tyrosinase__ gene, we generated and characterized two lines of transgenic mice that express Cre recombinase in m
Using gene-targeting methods, a progesterone receptor Cre knockin (PR-Cre) mouse was generated in which Cre recombinase was inserted into exon 1 of the PR gene. The insertion positions the Cre gene downstream (and under the specific control) of the endogenous PR promoter. As for heterozygotes for th