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Tamoxifen-induced cell death in malignant melanoma cells: possible involvement of the insulin-like growth factor-1 (IGF-1) pathway

✍ Scribed by Lena Kanter-Lewensohn; Leonard Girnita; Ada Girnita; Anica Dricu; Gunilla Olsson; Louise Leech; Gunnar Nilsson; Agneta Hilding; Johan Wejde; Kerstin Brismar; Olle Larsson


Book ID
117462469
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
232 KB
Volume
165
Category
Article
ISSN
0303-7207

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✍ Atsumi Nitta; Wen-Hua Zheng; RΓ©mi Quirion πŸ“‚ Article πŸ“… 2004 πŸ› John Wiley and Sons 🌐 English βš– 190 KB

## Abstract Corticosterone (CORT) is well known to induce neuronal damage in various brain regions including the hippocampus, but the precise mechanism(s) of action underlying these effects has yet to be fully established. Insulin‐like growth factor‐1 (IGF‐1) is a trophic factor promoting cell surv