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Involvement of ligand occupancy in Insulin-like growth factor-I (IGF-I) induced cell growth in osteoblast like MC3T3-E1 cells

✍ Scribed by Seok-Kwun Kim; Ji-Young Kwon; Taek-Jeong Nam

Book ID
112010844
Publisher
IOS Press
Year
2007
Tongue
English
Weight
188 KB
Volume
29
Category
Article
ISSN
0951-6433

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## Abstract We examined the relationship between signal transduction and the expression of insulin‐like growth factor I (IGF‐I), IGF‐I receptor level, and IGF binding proteins (IGFBPs) in murine clonal osteoblastic MC3T3‐E1 cells. 12–O‐Tetradecanoylphorbol‐13‐acetate (TPA), an activator of protein